Mayo Clinic Comprehensive Cancer Center in Florida
Oncology • Jacksonville, FL • Since 1889 • 1 site in Florida (Jacksonville) with broader national/international network locations
About
The Mayo Clinic is a leading non-profit medical center with major campuses in Rochester, Minnesota; Phoenix/Scottsdale, Arizona; and Jacksonville, Florida. It operates a large network including Mayo Clinic College of Medicine and Science, Mayo Clinic Health System, and Mayo Clinic Laboratories, and is renowned for tertiary care, high transplant volumes, and extensive research (over $660 million annually). The Jacksonville location (Mayo Clinic Hospital) is part of Mayo Clinic’s Florida campus network and offers expert cancer care as part of its comprehensive oncology services. If you’re seeking a Comprehensive Cancer Center specifically, Mayo Clinic’s cancer program in Jacksonville is integrated into the Florida campus system, with access to Mayo Clinic’s multidisciplinary oncology teams and research resources. For precise services, appointments, and oncology specialties at the Florida/Jacksonville site, contact Mayo Clinic Jacksonville directly or visit their Florida campus page.
Clinic Type
Oncology
Address
Jacksonville, Florida
Phone
904-953-2000
giftplanning@mayo.edu
Opening Hours
8 a.m. to 5 p.m. Eastern time Monday through Friday
Telehealth
Advanced Care at Home program delivers inpatient-quality care at home; Cancer Care Beyond Walls mentions home-based cancer treatment options
Services Offered
Technology & Equipment
Team
Insurance & Payment
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Mayo Clinic Comprehensive Cancer Center in Florida works with hundreds of insurance companies and is in-network for millions of people. In most cases, Mayo Clinic doesn't require a physician referral.
Languages Spoken
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FAQs
What services does Mayo Clinic Comprehensive Cancer Center Florida offer?
Comprehensive cancer care including oncology, hematology, radiation oncology, surgery, and access to clinical trials.
Costs and insurance
Mayo Clinic Comprehensive Cancer Center in Florida works with hundreds of insurance companies and is in-network for millions of people. In most cases, Mayo Clinic doesn't require a physician referral.
Awards & Accreditations
Social Media
Photos








What Patients Say
Overall sentiment across review platforms: positive
- CMS HCAHPS/Momentary Labs: 4/5 stars (947 surveys)
- U.S. News & World Report: 95% recommendation rate (Not explicitly stated)
- Yelp: 3.1/5 stars (229 reviews)
Patients praise
- Highly responsive medical staff and expert physician communication
- Efficient scheduling and appointment coordination across departments
- High cleanliness standards and hotel-like, modern facilities
- Effective patient portal for quick access to test results and records
- High patient willingness to recommend the facility
Common complaints
- Overwhelming anxiety in waiting areas despite facility quality
- Difficulty with initial online check-in processes for some patients
"My only regret is not having consulted Mayo from the beginning... The patient portal is amazing. Every dept I had contact with prior to my surgery was amazing."
— Mayo Clinic Connect Discussion"Walking into Mayo was an experience in itself—it felt more like a high-end hotel than a clinic... the moment the care team started talking, I felt a huge sense of relief."
— Mayo Clinic Connect DiscussionSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Mayo Clinic study demonstrates safety, feasibility of delivering chemotherapy at home - Mayo Clinic News Network — Mar 19, 2026
- First Lady Casey DeSantis Announces Florida Cancer Innovation Fund Project, Treats First Patient in the Florida Panhandle - Space Coast Daily — Feb 12, 2026
- FACCA Retreat Highlights Growing Power of Cancer Collaboration in Florida » Florida Academic Cancer Center Alliance — May 11, 2026
- Carbon Ion Therapy: A New Era in Precision Radiation - CancerConnect — Feb 9, 2026
- Florida becomes the first in the U.S. to offer carbon ion cancer therapy | FOX 35 Orlando — Jan 15, 2026
Information sourced from the clinic's website as of July 11, 2026.
More oncology clinics in Jacksonville
Summary: - Cancer Specialists of North Florida (CSNF) is a private medical practice and the largest cancer care provider in Jacksonville, Florida, with 12 offices across the U.S. (all in Florida) and a HQ in Jacksonville. - They offer patient assistance and funding support through a foundation and conduct research opportunities; they run fundraising campaigns to support cancer research and patient services. - Company size and reach: about 156 employees (+7.5% YoY, ~21 more staff) with annual revenue around $10.1M. LinkedIn presence with ~3.8k followers. - Locations: multiple addresses in the Jacksonville area and surrounding FL communities (examples include Jacksonville Beach, St. Augustine, Fleming Island, and Jacksonville). - Contact: main phone 1-904-306-9229; website link available viaCancerSpecialistsNF.com (for locations and services). If you’re looking for the CSNF home page specifically, navigate to their main site to view a complete list of locations, services, patient resources, and ongoing fundraising/foundation efforts.
Onslow Memorial Hospital (OMH) is a nonprofit, 162-bed hospital founded in 1944 and located in Jacksonville, North Carolina. It offers comprehensive oncology services along with a wide range of medical specialties, including dermatology, internal medicine, primary care, pulmonology, radiology, and surgical care. OMH operates a modern Cancer/Oncology program integrated with diagnostic imaging (MRI, CT, neurodiagnostics) and supportive services. The hospital is nationally accredited by The Joint Commission, has a skilled medical staff with 100+ doctors across 25+ specialties, and provides extensive inpatient/outpatient facilities, including an Emergency Department, Labor and Delivery, Neonatal Intensive Care Unit, ICU/CCU, and rehabilitation services. OMH engages in community and foundation activities and maintains multiple offices in Jacksonville, NC (HQ at 317 Western Blvd) with broader services and online health information resources. Contact: (910) 577-2345; privacyemail: privacyoffice@onslow.org.
Southeastern Medical Oncology Center (SMOC) is a North Carolina-based, physician-led cancer care provider established in 1984 and headquartered in Goldsboro. The center operates as a Hospitals and Health Care partnership with 1,000+ doctors across four U.S. offices and offers oncology/hematology services, clinical trials, and patient education. Key details: - Headquarters: Goldsboro, NC - Other locations: Clinton, NC; Jacksonville, NC (multiple offices) - Services: Oncology therapies, hematology, clinical trials, patient education - Size: 1,000+ doctors (organization-wide) - Contact: admin@cancersmoc.com; 800-849-0203 - Website: cancersmoc.com - LinkedIn: linkedin.com/company/cancersmoc If you’re specifically looking for SMOC in Jacksonville, NC: they operate a Jacksonville-area office and have posted hiring updates for the Greater Jacksonville region, indicating active clinical staffing and presence in that area.
Baptist MD Anderson Cancer Center is a nonprofit cancer treatment alliance in Jacksonville, Florida. A partner of Baptist Health and MD Anderson Cancer Center, it specializes in adult cancer care and offers prevention, screening, education, survivorship and support services. Founded in 1955, it operates five offices in the Jacksonville area, including its headquarters at 1301 Palm Ave, Jacksonville. The center emphasizes comprehensive cancer care across multiple locations and serves as part of the Jacksonville medical community. Contact: 844-632-2278 or 904-202-2092.
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