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About

Main Gastroenterology PC is a small gastroenterology and endoscopy practice based in Williamsville/Buffalo, NY. They offer gastroenterology care and diagnostic procedures with a focus on safe, patient-centered treatment. The practice operates with a two-person team led by owner Antonino Mannone and provides services from a Buffalo/Lackawanna area locale. Key details: - Location: Williamsville, NY (serving Buffalo area) - Services: Gastroenterology care and endoscopy - Team: 2 employees; Owner: Antonino Mannone - Contact: 716-631-8275 or 716-632-3577 - Tech: Medent software - Web presence: maingastro.com; modest online traffic and engagement If you’re looking for a gastroenterologist in Buffalo, this practice offers specialized GI care and endoscopic services with a small, patient-focused team.

Clinic Type

Gastroenterology

Address

Williamsville, NY (between Lancaster and Clarence)

Phone

716-632-3577

Email

maingastro8201@gmail.com

Opening Hours

Not published — contact the clinic to confirm hours.

Services Offered

Technology & Equipment

  • Colonoscopy
  • Sigmoidoscopy
  • Upper Endoscopy

Team

  • Antonino Mannone, MD, Board-certified gastroenterologist; has been practicing since 1984; affiliated with Millard Fillmore Suburban Hospital - Kaleida — Gastroenterologist / Endoscopist

Insurance & Payment

Languages Spoken

Photos

What Patients Say

Overall sentiment across review platforms: mixed

  • Healthgrades: 3.9/5 (26)
  • RateMDs: 3.8/5 (9)
  • Vitals: 4.7/5 (20)

Patients praise

  • Knowledgeable and intelligent physician
  • Warm and caring personality
  • Effective diagnostic and procedural skills
  • Does not rush appointments

Common complaints

  • Some patients reported the provider did not listen well
  • Concerns about being flooded with tests/screenings

"Dr. Mannone is a highly intelligent doctor with a warm personality, who truly values his patients-as people first."

RateMDs

"Avoided listening to patients... Would avoid this practice."

Healthgrades

"He is understanding and patient and does not rush your appoinrment. He answers all your questions with through explanations."

Vitals

Synthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].

Information sourced from the clinic's website as of July 11, 2026.

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