Houston Methodist Primary Care Group - Sienna
Family Medicine • Missouri City, TX • Since 1919
About
Summary: Houston Methodist Primary Care Group in Sienna/Missouri City is part of the Houston Methodist system, a large academic medical center headquartered at 6565 Fannin St, Houston. The system includes multiple hospitals and primary care locations across the Houston area, offering primary care services through a network of clinics. The flagship hospital is Houston Methodist Hospital (Texas Medical Center), established in 1919 and internationally recognized for specialties such as cardiovascular surgery, cancer, epilepsy treatment, and organ transplantation. The Houston Methodist network expanded to include 13 U.S. offices and numerous locations, with the system rebranded as Houston Methodist in 2013.
Clinic Type
Family Medicine
Address
8330 Hwy. 6, Suite 110, Missouri City, TX 77459
Phone
//281.276.0653
HMG@houstonmethodist.org
Opening Hours
M-F 8 a.m. – 5 p.m.
Services Offered
Insurance & Payment
—
Languages Spoken
FAQs
What are the office hours?
Office Hours M-F 8 a.m. – 5 p.m.
Social Media
Photos

What Patients Say
Overall sentiment across review platforms: mixed
- Zocdoc (Same Day Clinic Sienna): 4.56/5 (9 reviews)
Patients praise
- Professional and attentive physicians
- Convenience of services for routine and preventative care
Common complaints
- Difficulties reaching doctors directly via phone
- Administrative/billing issues including insurance verification errors
- Long wait times for appointments
- Reports of unprofessionalism among some staff members
"I can NOT directly call my doctor's office and have to go to call their main number and ask them to relay my message to my doctor which sometime takes a couple of days to receive a response."
— LocalityBiz review"The staff could be heard laughing at patients situations. I could hear inappropriate conversations about patients."
— LocalityBiz reviewSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Dr. Li Cai, MD - Internist in Houston, TX | Healthgrades — Oct 23, 2025
- Dr. Elisa Kim, MD - Family Medicine Physician in Houston, TX | Healthgrades — Sep 23, 2025
- Hsin Li, DO, MPH - Cypress, TX - Family Medicine Physician | Doctor.com — Aug 28, 2025
- Houston Medics now offering primary care in Missouri City | Community Impact — Jun 10, 2026
- Houston Methodist pledges $10M to expand uninsured, underinsured health care access | Sugar Land - Missouri City | Community Impact — Feb 24, 2026
Information sourced from the clinic's website as of July 11, 2026.
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