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About

Prisma Health Gastroenterology and Liver Center – Simpsonville is part of Prisma Health, South Carolina’s largest nonprofit health system. The center focuses on digestive health services, including gastroenterology and liver care, and is aligned with Prisma Health’s mission to improve clinical quality, access, and patient experience across South Carolina. The organization operates from its Greenville HQ and serves patients statewide through its facilities and programs. For specifics on Simpsonville services, availability, or appointment information, contact Prisma Health directly or visit prismahealth.org.

Clinic Type

Gastroenterology

Address

741 SE Main St. Simpsonville, SC 29681

Phone

864-522-8420

Email

careers@prismahealth.org

Opening Hours

8 AM–5 PM

Services Offered

  • Gastroenterology
  • Hepatology
  • Endoscopy

Technology & Equipment

  • Endoscopy suite on-site

Team

  • M. Macmillan, MD — Gastroenterologist
  • P. Sentell — Gastroenterologist
  • Sentell, AGAC, AGAC — Gastroenterologist

Insurance & Payment

Languages Spoken

Photos

What Patients Say

Overall sentiment across review platforms: mixed

  • Prisma Health Find a Doctor portal: Individual providers at the facility generally hold high ratings (e.g., 4.6–4.9 out of 5 stars based on dozens of reviews per provider) (Varies by provider (e.g., 12 to 29 reviews per provider listed))

Patients praise

  • Professional and knowledgeable clinical staff (e.g., Physician Assistants)
  • Clear communication during follow-up visits

Common complaints

  • Difficulty reaching staff by phone or getting return calls
  • Billing and insurance coding disputes (e.g., diagnostic vs. routine coding)
  • Perceived lack of helpfulness from clinical staff

"I give one star because I can never get anyone on the phone to make an appointment stayed on hold the first time for 45 minutes and another time for 30 minutes."

LocalityBiz review

"For the follow up I saw PA John Colton. He explained everything in laymens terms, answered all my questions and took his Time with me... I felt I was heard and presented as very knowledgeable and genuinely cared."

LocalityBiz review

Synthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].

Information sourced from the clinic's website as of July 11, 2026.

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Simpsonville, SC·Gastroenterology

Gastroenterology Associates is a private, physician-led medical practice specializing in digestive system diseases, with 11 offices across Upstate South Carolina and 4 endoscopy centers. Founded in 1978 and headquartered in Greenville, SC, the practice offers prompt evaluation, diagnosis, and treatment, including in-house labs and advanced endoscopy. They emphasize timely care (urgent cases seen within 24 hours) and low-cost, high-quality services. Key locations include Simpsonville (317 St. Francis Drive Suite 150) and Greenville offices, with additional sites in Spartanburg, Clemson, and more. They employ about 49 people and reported annual revenue around $10.6 million.

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Simpsonville, SC·Gastroenterology

Summary: The page describes Internal Medicine Associates of Greenville, a Prisma Health medical practice focused on prevention, diagnosis, and treatment of illnesses and chronic diseases. It operates as a partner in the Medical Practices industry, with 2 offices (Greenville, SC HQ at 1025 Verdae Blvd; Tuscaloosa, AL) and presence in the United States. While the practice specializes in internal medicine, the provided content does not list gastroenterology services or doctors in Simpsonville, SC. If you’re seeking gastroenterology specifically in Simpsonville, this page does not confirm services there; you may want to search Prisma Health gastroenterology offerings or the Simpsonville-area doctor directory for GI specialists. For direct GI care, consider Prisma Health affiliated gastroenterologists in the Greenville area or nearby cities. Contact: 864-240-8104, 864-242-4683, or +1 205-349-4200.

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