Prisma Health Internal Medicine–Simpsonville
Internal Medicine • Simpsonville, SC
About
Prisma Health Internal Medicine – Simpsonville is the Simpsonville service location of Prisma Health’s Internal Medicine practice. The broader organization, Internal Medicine Associates of Greenville, is a medical practices partnership headquartered in Greenville, SC, with 2 US offices and a focus on prevention, diagnosis, and treatment of illnesses and chronic conditions. Primary contact details for related locations include multiple phone lines and a Greenville HQ address; the Tuscaloosa office appears under aliases. For Simpsonville-specific details (address, hours, providers), please refer to Prisma Health’s official site or contact numbers.
Clinic Type
Internal Medicine
Address
727 SE Main St. Suite 300, Simpsonville, SC 29681
Phone
+1 864-522-1170
careers@prismahealth.org
Opening Hours
8 AM–5 PM
Services Offered
Insurance & Payment
—
Languages Spoken
—
FAQs
Referral Not Required
- Book Online- Accepting New Patients
Social Media
Photos




What Patients Say
Overall sentiment across review platforms: mixed
- Multiple platforms (Prisma Health, Vitals, Yelp, LocalityBiz): 4.94/5 (via Prisma Health internal aggregate)
Patients praise
- Some patients report excellent and thorough care from specific providers
- Recognition of staff friendliness and professional demeanor in certain instances
- Appreciation for proactive follow-up care by some office staff
Common complaints
- Difficulty scheduling or rescheduling appointments
- Long wait times in the office
- Concerns regarding bedside manner or feeling unheard by some providers
- Communication issues regarding test results or medical instructions
- Challenges with administrative processes, such as registration or referral policies
"Seems like no matter which doctor I see at this particular phacility they want to get you in and out quickly and they are extremely hard to reach outside of your five minute appointment that you end up paying a lot of money for."
— Patient review on LocalityBiz"I just wish they'd told me that they couldn't treat me when I initially called and not wasted a trip (and $) to be told they were referring me."
— Patient feedback on Prisma Health provider profile"This office is way more on the ball with followup needs than anywhere I've ever been. I look forward to my next visit and their care."
— Patient review on LocalityBizSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Rachel Annette Robinson, FNP - Simpsonville, SC - Internal Medicine, Pediatrics - Book Appointment — Mar 27, 2026
- Lauren Bowers Glass, FNP - Simpsonville, SC - Family Medicine - Book Appointment — May 2, 2026
- Dr. Eric Farquis Knapp, MD - Simpsonville, SC - Family Medicine - Book Appointment — May 2, 2026
- April Simpson — May 8, 2026
- Dr. Ashley Pollock Trexler, MD - Greenville, SC - Internal Medicine - Book Appointment — May 2, 2026
Information sourced from the clinic's website as of July 11, 2026.
More internal medicine clinics in Simpsonville
Summary: - Prisma Health Internal Medicine Associates of Greenville is a medical practice specializing in prevention, diagnosis, and treatment of a wide range of conditions, including chronic diseases and common illnesses. - Located in Greenville, SC (HQ: 1025 Verdae Blvd, Greenville, SC 29607) with a second office in Tuscaloosa, AL; overall practice serves the Upstate region of South Carolina. - The practice has about 110 employees and operates as a partnership within Prisma Health, offering services across internal medicine subspecialties (medicine, gastroenterology, rheumatology, endocrinology) and general primary care. - Contact: 864-240-8104, 864-242-4683; email imatuscweb@gmail.com. - Online presence: prismahealth.org/locations/practices/internal-medicine-associates-of-greenville; LinkedIn: /prisma-health-internal-medicine-associates-of-greenville. - Aliases include Internal Medicine Associates of Greenville and Internal Medicine Associates of Tuscaloosa, P.C. Note: The listing does not specify a Simpsonville, SC location. If you’re seeking internal medicine near Simpsonville, you may want to search Prisma Health locations in the Simpsonville area or nearby Greenville offices.
Grace Internal Medicine is a small medical practice based in Morristown, Tennessee, with a presence in the Philippines. They operate in the Medical Practices industry and have 7 employees, generating an annual revenue between $1 million and $5 million. Their team includes a mix of medical, operations, and customer service staff, with most staff located in the United States and a minority in the Philippines. The company appears to offer remote patient monitoring among its technology offerings and has a 5.0/5.0 employer rating from 1 review. Important note for your specific query: The listing does not indicate a Grace Medical Clinic in Simpsonville or explicit ties to “Internal Medicine and Primary Care” under a Simpsonville location. If you’re seeking internal medicine and primary care services in Simpsonville, you may want to verify whether Grace Internal Medicine has a local clinic there or look for a different practice explicitly listing Simpsonville, SC, as a location.
Comparing your options?
See other internal medicine clinics in Simpsonville, or search the full directory by insurance, ratings, and more.

