Avera Cancer Institute — Prairie Center, Sioux Falls, SD
Oncology and Hematology • Sioux City, IA • Since 1911
About
Avera Cancer Institute – Prairie Center is part of Avera McKennan Hospital & University Health Center, a nonprofit health system based in Sioux Falls, SD. The Prairie Center offers cancer care services as a specialty within the broader Avera network, serving patients in Sioux Falls and surrounding areas (including nearby regions such as Sioux City). The system provides comprehensive cancer treatment, leveraging Avera’s multidisciplinary approach and regional care footprint. For specific services, physicians, appointment details, and proximity, contact Avera Cancer Institute or visit the Avera locations site.
Clinic Type
Oncology and Hematology
Address
1000 E 23rd St, Suite 340, Sioux Falls, SD 57105, US
Phone
+16053223000
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Opening Hours
Not published — contact the clinic to confirm hours.
Emergency Care
24/7 Patient Navigation
Services Offered
Team
Insurance & Payment
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Languages Spoken
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FAQs
What services are included under Specialty Oncology Services?
The page references Specialty Oncology Services and Hematology Oncology under Avera Cancer Institute—Sioux Falls, but does not list specific services in the provided excerpt.
Awards & Accreditations
Social Media
Photos






What Patients Say
Overall sentiment across review platforms: mixed
- Birdeye (Avera Medical Group Oncology & Hematology): 1.7/5 stars (6 reviews)
- Birdeye (Avera Breast Center): 4.5/5 stars (8 reviews)
- Birdeye (June E. Nylen Cancer Center - Sioux City): 4.2/5 stars (150 reviews)
Patients praise
- Knowledgeable, friendly, and caring staff and physicians
- Effective communication and explanation of diagnoses by specific providers
- Comprehensive support and collaborative approach to cancer care
- Helpful and supportive nursing and administrative teams
Common complaints
- Communication issues between clinic locations
- Frustrations with appointment scheduling and wait times
- Concerns regarding quality of care and medical knowledge in specific instances
- Perceived lack of support or responsiveness to patient needs in some cases
"Communication is terrible between locations. When scheduling issues are brought to their attention you are treated like you are the problem."
— Birdeye review of Avera Medical Group Oncology & Hematology — Prairie Center"Dr. Jones was nothing short of amazing. He explained everything completely and answered all my questions. I would highly recommend him!"
— Avera physician profile patient comment"I have never encountered a frown or frustration. We cancer patients can require much compassion and it is always given."
— Birdeye review of June E. Nylen Cancer Center in Sioux CitySynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Avera's cancer specialization is a win for patients, physicians - SiouxFalls.Business — Apr 2, 2026
- Avera Health celebrates National Cancer Survivors Day — Jun 7, 2026
- The Impact of Local Cancer Care for Avera Patients — Jul 29, 2025
- Avera Medical Minute: Clinical Trials for Cancer Expand Across Avera Footprint — Aug 19, 2025
- Ninth annual Cancer Comfort Collection drive bittersweet for SD woman — Oct 24, 2025
Information sourced from the clinic's website as of July 11, 2026.
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