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About

Avera Cancer Institute – Prairie Center in Sioux Falls, SD is part of Avera McKennan Hospital & University Health Center. It offers comprehensive cancer care within the Avera system, serving the Sioux Falls area and surrounding states. Key points: - Part of a nonprofit health system headquartered in Sioux Falls, SD (founded 1911). - Focus areas include cancer care, medical specialties, and integrated health services. - Contact: multiple local phone numbers available via the Avera locations site. - Located within the Avera Prairie Center campus in Sioux Falls, connected to the broader Avera network (including Avera Digestive Health Center and other specialty services).

Clinic Type

Oncology

Address

1000 E 23rd St, Suite 340, Sioux Falls, SD 57105, US

Phone

+16053223000

Email

Opening Hours

Not published — contact the clinic to confirm hours.

Emergency Care

24/7 Patient Navigation

Services Offered

  • oncology
  • cancer treatment
  • medical oncology
  • hematology
  • cancer care

Insurance & Payment

Languages Spoken

Awards & Accreditations

  • QOPI Certification Program accreditation; COCA/ASCO accreditation (COC and QOPI)

Photos

What Patients Say

Overall sentiment across review platforms: mixed

  • Avera Medical Group Oncology & Hematology — Prairie Center: 1.7 out of 5 stars (6 reviews (Birdeye/Google aggregation))
  • Avera Breast Center — Prairie Center: 4.5 out of 5 stars (8 reviews (Birdeye/Google aggregation))
  • Avera Medical Group Gynecologic Oncology — Prairie Center: 4 out of 5 stars (1 review (Birdeye/Google aggregation))

Patients praise

  • High praise for individual physicians for being knowledgeable, kind, and compassionate
  • Staff described as friendly, supportive, and caring by many patients
  • Appreciation for thorough explanations and effective treatment journeys
  • Success in multidisciplinary care and clinical trials

Common complaints

  • Communication issues between clinic locations and departments
  • Concerns about scheduling reliability and coordination
  • Reports of difficulty accessing certain services or finding veins for IVs
  • Complaints regarding perceived lack of empathy or responsiveness to patient needs in specific instances

"Dr. Jason Jones has always been professional, concerned and friendly in all my appts. Highly recommend him! The staff has been wonderful support and caring individuals! They show they care and have humor."

Avera Physician Profile Testimonial

"Communication is terrible between locations. When scheduling issues are brought to their attention you are treated like you are the problem."

Birdeye Patient Review

"I am a patient of an Avera specialist doctor who is treating my rare cancer, after my diagnosis I turned to the Avera Cancer Institute for support but was denied all of their services... I have started to move my doctors away from Avera because they are no longer the caring hospital they used to be."

LocalityBiz Patient Review

Synthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].

Information sourced from the clinic's website as of July 11, 2026.

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