Palmetto Endocrinology: Endocrinology, Diabetes and Thyroid ...
Endocrinology • Summerville, SC • Since 2014
About
Palmetto Endocrinology is a private endocrinology practice in Summerville, SC, with a second location in Ladson. Led by Dr. Joseph Mathews, the clinic specializes in endocrine, thyroid, and diabetes care, offering services for weight loss, PCOS, Hashimoto’s, adrenal and parathyroid disorders, male hypogonadism, and related conditions. They perform office-based ultrasound-guided procedures (ECNU-certified) and may host clinical trials to provide access to the latest treatments. The practice serves patients from across the region, including out-of-state referrals, and operates from two South Carolina offices. Contact: multiple local phone lines are available.
Clinic Type
Endocrinology
Address
1101 Old Trolley Road #300, Summerville, SC 29485; 3496 Iron Horse Road, Ladson, SC 29456
Phone
8433762670
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Opening Hours
Not published — contact the clinic to confirm hours.
Services Offered
Technology & Equipment
Team
Insurance & Payment
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We accept most major insurance plans
Languages Spoken
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Photos








What Patients Say
Overall sentiment across review platforms: mixed
- Official Practice Website: 4.89 out of 5 stars (based on their internal testimonial count) (122 (internal website count))
- WebMD: 5.0 (based on 7 reviews) (7)
- Yelp: Not specified numerically (12)
Patients praise
- Dr. Joseph Mathews is frequently praised for his expertise, clinical knowledge, and life-changing care for complex conditions like thyroid cancer and rare disorders
- Patients appreciate the doctor's willingness to listen and spend time during consultations
- Successful treatment outcomes reported by some patients
Common complaints
- Rudeness and lack of professionalism from front office staff
- Difficulty reaching the office via phone or getting timely responses to messages
- Long wait times for appointments and administrative delays (e.g., lab orders, medication refills)
- Frustration with being handed off to Physician Assistants/Nurse Practitioners instead of the lead physician
"Dr. Mathews, as others have said, has saved and changed my life... He is so knowledgeable and kind. I trust him completely."
— Doctor.com Review"The doctors are good and the staff are friendly but they really need more help with answering the phone. I have called at several different times of the day and no one ever picks up... It’s ridiculous."
— LocalityBiz Review"The front office staff are extremely rude and make all interactions feel like a bother. The worst, and most unacceptable part, is I often run out of medication."
— Healthgrades ReviewSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Temple W. Simpson, PA - Physician Assistant in Summerville, SC — May 14, 2026
- Ascension Sacred Heart Emerald Coast Brings Endocrinology Care Close to Home - South Walton Life | 30A News, Events and Community Information — Feb 7, 2026
- Dr. Whitney Winn Brown, MD - Columbia, SC - Pediatric Endocrinology, Pediatrics - Book Appointment — May 23, 2026
- Personalized Weight Loss in Summerville: What To Expect from GLP-1 Programs — Feb 24, 2026
- Weight Loss Medications: How GLP-1s Support a Healthy Lifestyle — Nov 25, 2025
Information sourced from the clinic's website as of July 11, 2026.
More endocrinology clinics in Summerville
Magnolia Endocrinology, LLC is a small endocrine-focused practice in the United States, founded in 2017. It operates as a partnership with 2 employees and specializes in endocrinology, diabetes and metabolism, including conditions like hypogonadism, thyroid disease, diabetes, and calcium disorders. The co-founder and managing partner is Charles J. Mewshaw. Contact numbers are (843) 900-0495 and 854-201-1983. The practice has a modest web presence (magnoliaendocrinology.com) and about 2,536 monthly visits. It appears to serve the U.S. market (Top country: United States) with general management and medical staff. Notes: The provided data does not specify Summerville, Goose Creek, or Moncks Corner locations; no explicit local address is listed.
Summary: - The MUSC Health Endocrinology program at Nexton Medical Park in Summerville is part of MUSC Health, South Carolina’s comprehensive academic health system affiliated with the Medical University of South Carolina. - MUSC Health emphasizes high-quality, safe patient care and education across multiple locations in South Carolina, with a network that includes 16 US offices and a wide range of clinical services. - For specific endocrine services, locations, providers, and appointment details at Nexton Medical Park (Summerville), visit muschealth.org or contact MUSC Health directly to confirm current endocrinology offerings, provider availability, and scheduling.
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