Roper St. Francis Express Care - Urgent Care in Charleston, SC
Urgent Care • Charleston, SC • Since 1829 • Multiple Express Care locations in the Charleston region locations
About
Roper St. Francis Express Care is the urgent care division of Roper St. Francis Healthcare, a nonprofit health system based in Charleston, SC. It offers fast, walk-in urgent care services in the Charleston area and has earned local recognition (Best Urgent Care by Charleston City Paper 2026). The broader Roper St. Francis network includes hospital-level services (cancer care, heart and vascular, orthopedics, women's services, rehabilitation) and a physician network across multiple South Carolina locations. The organization employs about 1,904 staff, is headquartered at 316 Calhoun Street, Charleston, and traces its roots to 1829.
Clinic Type
Urgent Care
Address
Express Care - Maybank Hwy, 3575 Maybank Hwy, Suite A, Johns Island, SC 29455
Phone
843-203-2246
MercyHealth_HR_Service_Center@mercy.com
Opening Hours
Open daily 8 a.m. – 8 p.m. (some holidays apply: closed Thanksgiving Day, Christmas Day, New Year’s Day)
Emergency Care
Available at Express Care for urgent issues; if life-threatening, call 911 or go to emergency room
Services Offered
Insurance & Payment
—
Walk-in, Save your place in line (priority queuing)
Languages Spoken
—
FAQs
What does Express Care treat?
Most minor illnesses and injuries (e.g., allergies, asthma, bone/joint injuries, bug bites, bronchitis, colds/flu, cuts, earaches, on-site testing and labs, stomach pains, sore throat, UTIs)
What are the hours?
8 a.m. – 8 p.m. daily, with some holidays noted as closed
What issues do Express Care services cover?
Express Care services are for common, urgent issues that need same-day treatment and may include on-site testing for COVID, flu, strep, and physicals.
How can I reduce wait time?
Walk in or save your place in line online to reduce wait.
Are there evening or weekend hours?
Yes, Express Care offers weekend and evening hours.
How to get directions or book online?
Each location provides Get Directions and Book Online options.
What if I have a more serious condition?
Express Care is part of a larger network; if needed, you can be connected to specialists within the network.
Social Media
Photos








What Patients Say
Overall sentiment across review platforms: positive
- Solv (Folly Rd location): 4.8/5 (1,661 reviews) (1,661)
- Birdeye (Folly Rd/General): 4.4/5 (1,093 reviews) (1,093)
- Solv (West Ashley Circle location): 4.7/5 (661 reviews) (661)
- Birdeye (North Charleston/Main St location): 4.5/5 (1,231 reviews) (1,231)
Patients praise
- Efficient and quick service for many patients
- Professional, kind, and compassionate staff
- Ease of scheduling via online booking systems
- Effective care and treatment plans
Common complaints
- Longer than expected wait times
- Instances of perceived poor bedside manner from some providers
- Occasional concerns regarding facility cleanliness
"Even though the waiting room was packed I was seen within 15 minutes and all tests were prompt. Clean and efficient!"
— Solv review"Scheduling, front desk and nurse were all amazing and great experience. Dr care was less than desirable and made me feel as if I should not come back and should have never come in, in the first place."
— Solv review"I had a great experience during my visit today. The doctor’s care was outstanding, and the team that attended to me... was compassionate and caring."
— Solv reviewSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
- Roper St. Francis Express Care on International Blvd to close permanently this Friday — Nov 11, 2025
- Flu season facts from an Infection Prevention Physician - Roper St. Francis Healthcare | Health News Blog | Charleston, SC — Jan 9, 2026
- New health pavilion brings emergency care, imaging services to Summerville — Jun 16, 2026
- HCA Healthcare secures six Lowcountry clinics — Jun 7, 2026
- Roper St. Francis Healthcare’s new Health Pavilion at Sawmill Centre expands emergency, lab, imaging services for Summerville community - Who's On The Move — Jun 18, 2026
Information sourced from the clinic's website as of July 11, 2026.
More urgent care clinics in Charleston
Summary: MUSC Health offers 24/7 urgent care and emergency services, with virtual visits available through the MUSC Center for Telehealth. The Center (founded 2014) is a state-wide telehealth headquarters and a national Telehealth Center of Excellence, enabling expert care access across South Carolina via remote video, store-and-forward, and remote monitoring. Based in Charleston, SC, the Center collaborates with MUSC Health and statewide providers to deliver high-quality urgent and emergency care through telehealth, education, and simulation. Contact: telehealthinfo@musc.edu | 843-792-1414.
Summary: CAMC (Charleston Area Medical Center) is a nonprofit, teaching hospital system headquartered in Charleston, WV. It operates multiple campuses (Memorial Hospital, General Hospital, Women and Children’s Hospital, Teays Valley Hospital, and Greenbrier Valley Medical Center) plus a network of facilities across West Virginia. It provides extensive emergency and urgent care services and hosts walk-in, inpatient, and outpatient care across its campuses. For walk-in/urgent care options, CAMC offers immediate-access services at its Charleston-area facilities and affiliated campuses, with comprehensive acute care, specialty services (cardiac, oncology, neurology, orthopedics, trauma, and obstetrics), and 24/7 emergency department coverage. If you need convenient walk-in care in Charleston, consider CAMC Memorial or CAMC General Hospital locations, as well as CAMC Teays Valley (Putnam County) for nearby urgent care access. For exact hours and walk-in availability, check CAMC’s website or contact their Charleston locations directly.
Comparing your options?
See other urgent care clinics in Charleston, or search the full directory by insurance, ratings, and more.

