South San Francisco Clinic - San Mateo County Health
Primary Care • South San Francisco, CA • Since 1923
About
Summary: The San Mateo Medical Center is a government-backed, integrated hospital and clinic system serving San Mateo County as part of San Mateo County Health. It operates as a public health and clinical services provider with 2 offices in the United States (HQ: 222 West 39th Ave, San Mateo, CA 94403). It employs about 393 staff and reports roughly $473.4M in annual revenue. While the page highlights its role in public health and clinical services, it does not provide specific information about a separate “South San Francisco Clinic” function or location. If you’re looking for services specifically in South San Francisco, you may want to check San Mateo County Health’s site or contact the centers directly for clinic locations, hours, and care options in South San Francisco.
Clinic Type
Primary Care
Address
South San Francisco Clinic, South San Francisco, CA
Phone
(650) 877-7070
info-hcu@smcgov.org
Opening Hours
Monday – Friday: 8:00 a.m. – 5:00 p.m. (Extended pediatrics hours on Mondays and Wednesdays: 5:00 p.m. – 8:00 p.m.)
Services Offered
Insurance & Payment
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Languages Spoken
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FAQs
How do I make an appointment?
Make an appointment at the South San Francisco Clinic by calling (650) 877-7070. New patients can call the New Patient Connection Center at (650) 372-3200 to make the first appointment.
Social Media
Photos

What Patients Say
Overall sentiment across review platforms: mixed
Patients praise
- Some patients find appointment scheduling to be quick and accommodating in specific instances
- Acknowledgment that the staff may be working in difficult, high-demand, and under-resourced conditions
Common complaints
- Difficulty with appointment scheduling, including long wait times for appointments and last-minute rescheduling challenges
- Reports of poor patient care coordination, specifically regarding prescription refills
- Communication issues, including difficulty reaching staff by phone and lack of timely appointment confirmations or follow-ups
- Long wait times when visiting the clinic in person despite having an appointment
- Concerns regarding staff capacity and feeling overwhelmed at the facility
- Patient perception of judgmental interactions with providers
Synthesized from public review platforms as of Jul 10, 2026 — sources: [1][2][3][4].
In the News
- Topping off marks milestone at North County Wellness Center in South San Francisco | California Construction News — Aug 17, 2025
- Trump budget cuts trigger five Planned Parenthood closures in California — Jul 25, 2025
- Federal cuts trigger Planned Parenthood closures in the Bay Area – NBC Bay Area — Jul 27, 2025
- Planned Parenthood Closes South San Francisco Location, Four Others Due to Trump Budget Cuts — Jul 25, 2025
- San Mateo Medical Center Health Campus Completes Major Renovation & Expansion | County of San Mateo, CA — Dec 12, 2025
Information sourced from the clinic's website as of July 10, 2026.
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